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  2. USMLE Step 1
  3. Pharmacology: Autonomic Nervous System
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USMLE Step 1

High-yield board prep across pharmacology, biochemistry, and microbiology.

Medicine
PShared by Priya Nair
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Pharmacology: Autonomic Nervous System

Cholinergic and adrenergic receptors, agonists, and antagonists.

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Content

43 total questions

MCQ: 10
Fill-in: 8
Flashcards: 15
Pair match: 10
Pharmacology: Autonomic Nervous System – Flashcards
Flashcards

Card #1

Which receptor does acetylcholine act on at the neuromuscular junction?

Card #2

Muscarinic M2 receptor activation in the heart causes…

Card #3

Beta-1 (β1) adrenergic stimulation primarily affects…

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Pharmacology: Autonomic Nervous System – MCQ
Multiple Choice Questions
  1. 1. A drug causes bronchodilation and skeletal muscle tremor. Which receptor is most likely stimulated?

    • β2-adrenergic
    • β1-adrenergic
    • α1-adrenergic
    • Muscarinic M3
  2. 2. Atropine overdose classically presents with:

    • Dry mouth, dilated pupils, tachycardia, flushed skin
    • Salivation, miosis, bradycardia, sweating
    • Bronchospasm and diarrhea
    • Flaccid muscle paralysis
  3. 3. Postganglionic sympathetic neurons release which neurotransmitter at most target organs?

    • Norepinephrine
    • Acetylcholine
    • Dopamine
    • GABA
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Pharmacology: Autonomic Nervous System – Fill-in-the-blank
Fill in the Blank
  1. 1. Acetylcholine acts on ___ receptors at every autonomic ganglion.

    Answer:nicotinicalso: Nn, nicotinic (Nn)

    Hint: Ligand-gated ion channels

  2. 2. The adrenal medulla is innervated by ___ sympathetic fibres and releases mostly epinephrine.

    Answer:preganglionic

    Hint: There is no second neuron in the chain

  3. 3. Beta receptors couple to the ___ G protein, raising intracellular cAMP.

    Answer:Gsalso: G-s, Gs protein, G s

    Hint: The stimulatory one

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Pharmacology: Autonomic Nervous System – Pair match
Pair Match
Propranolol↔Nonselective beta antagonist
Metoprolol↔Selective β1 antagonist
Albuterol↔Selective β2 agonist; bronchodilator
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